RESEARCH ARTICLE
The Renin Angiotensin System and the Metabolic Syndrome
Chih-Hong Wang, Feng Li, Nobuyuki Takahashi*
Article Information
Identifiers and Pagination:
Year: 2010Volume: 3
First Page: 1
Last Page: 13
Publisher Id: TOHYPERJ-3-1
DOI: 10.2174/1876526201003010001
Article History:
Received Date: 12/02/2010Revision Received Date: 08/04/2010
Acceptance Date: 19/04/2010
Electronic publication date: 25/6/2010
Collection year: 2010
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
The renin angiotensin system (RAS) is important for fluid and blood pressure regulation. Recent studies suggest that an overactive RAS is involved in the metabolic syndrome. This article discusses recent advances on how genetic alteration of the RAS affects cardiovascular and metabolic phenotypes, with a special emphasis on the potential role of angiotensin-independent effects of renin.