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The Renin Angiotensin System and the Metabolic Syndrome

Chih-Hong Wang, Feng Li, Nobuyuki Takahashi

The renin angiotensin system (RAS) is important for fluid and blood pressure regulation. Recent studies suggest that an overactive RAS is involved in the metabolic syndrome. This article discusses recent advances on how genetic alteration of the RAS affects cardiovascular and metabolic phenotypes, with a special emphasis on the potential role of angiotensin-independent effects of renin.

June 25, 2010

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